The present study aimed to evaluate patients who were referred to adult allergy clinic due to allergic reactions after Cakes concomitant multiple intravenous-drug administrations in Emergency Department (ED).Between January 2017 and January 2019, patients admitted to our allergy clinic with hypersensitivity reactions to intravenous drugs administered in ED were included retrospectively.Fifty-seven patients who developed allergic reactions after intravenous drug administration in EDs were evaluated.Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) were the most common cause of allergic reactions (n = 40, 70.
2%).Skin Prick Tests (SPT) were positive in 6 (10.5%) patients.Drug Provocation Tests (DPT) were positive in 10 (17.
5%) patients.No significant correlation was found between the total number of drugs in the intravenous fluid and the degree of allergic reaction (r = -0.145, p = 0.282).
There was no statistically significant difference between the degree of allergic reaction and history of atopic disease (p = 0.579).In conclusion, concomitant administration of multiple drugs in intravenous fluids may Tridonic EC 30 C502K increase the risk of allergic reactions.